hrp0092p1-355 | Fat, Metabolism and Obesity (2) | ESPE2019

A Comparison of Insulin Resistance Indices: HOMA and Belfiore in 6-8-Year-Old, Properly Growing Children, Born Small for Gestational Age

Stawerska Renata , Lupinska Anna , Szalapska Malgorzata , Kolasa-Kicinska Marzena , Smyczynska Joanna , Hilczer Maciej , Lewinski Andrzej

Introduction: It is well known that low birth weight in children (born small for gestational age, SGA) predisposes them to the occurrence of obesity, insulin resistance (IR) and lipid disorders, observed even through the whole first decade of life. Thus, early diagnostics and prevention are very important. The HOMA index is used to assess insulin resistance (IRIHOMA). However, in some cases, high, prolonged postprandial insulin secretion is observed...

hrp0092p2-242 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Evaluation of the of Alpha2-Adrenergic Receptors Stimulation Effect on Prolactin Secretion, Based on the Result of the Test with Clonidine Used in the Diagnosis of Children with Short Stature

Kolasa-Kicinska Marzena , Stawerska Renata , Lupinska Anna , Smyczynska Joanna , Hilczer Maciej , Lewinski Andrzej

Introduction: Prolactin (Prl) - secreting cells and growth hormone (GH) - secreting cells are derived from the common somatomammotropic cells. Prl secretion depends primarily on the inhibitory effects of dopamine and the stimulatory effects of TRH and estrogens. The effects of other factors, especially the stimulation of the adrenergic system, are not well recognized. It is known that presynaptic stimulation of the alpha2-adrenergic receptor results in suppres...